Map2k6 ELISA Kit for Mouse(Mus musculus) | EIAab.comMap2k6 ELISA Kit for Mouse(Mus musculus)

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Map2k6 (Gene name),

Dual specificity mitogen-activated protein kinase kinase 6 (Protein name ), MP2K6_MOUSE from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Map2k6(Prkmk6;Sapkk3);

Protein name:

Dual specificity mitogen-activated protein kinase kinase 6(MAP kinase kinase 6;MAPKK 6);

Alternative:

SAPKK3;MAPK/ERK kinase 6(MEK 6);

Organism:

Mouse (Mus musculus).

General Annotation

Sub Unit:

N/A

Function:

Catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in MAP kinase p38 exclusively.

Subcellular Location:

N/A

Protein Attributes:

Sequence length:

334

Sequence:

50:

100:

150:

200:

250:

300:

334:

ERPTYPELMQ | HPFFTVHESK | AADVASFVKL | ILGD

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

SMR:

P70236

String:

P70236

Pfam:

PF00069

KEGG:

mmu:26399

UniGene:

Mm.14487

Uniprot:

P70236

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ELISA Kit for Mouse MAP kinase kinase 6

Cat.:

E1721h

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Manual:

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MSDS:

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96T

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ELISA Kit for Mouse MAP kinase kinase 6

Cat.:

E1721m

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96T

ELISA Kit for Mouse MAP kinase kinase 6

Cat.:

E1721b

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96T

CLIA Kit for Mouse MAP kinase kinase 6

Cat.:

U1721h

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Packing:

96T

CLIA Kit for Mouse MAP kinase kinase 6

Cat.:

U1721b

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MSDS:

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Packing:

96T

CLIA Kit for Mouse MAP kinase kinase 6

Cat.:

U1721m

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96T

Polyclonal Antibody for Mouse MAP kinase kinase 6

Cat.:

P1721Rb-m

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Packing:

40ug/0.2ml

Polyclonal Antibody for Mouse MAP kinase kinase 6

Cat.:

P1721Rb-h

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Packing:

40ug/0.2ml

Monoclonal Antibody for Mouse MAP kinase kinase 6

Protein for Mouse MAP kinase kinase 6

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

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References

1.

"Purification and cDNA cloning of SAPKK3, the major activator of RK/p38 in stress- and cytokine-stimulated monocytes and epithelial cells."
Cuenda A. , Alonso G. , Morrice N. , Jones M. , Meier R. , Cohen P. , Nebreda A.R.
EMBO J.15:4156-4164(1996) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
2.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
strain: C57BL/6.
tissue: Eye.
3.

"Differential involvement of p38 mitogen-activated protein kinase kinases MKK3 and MKK6 in T-cell apoptosis."
Tanaka N. , Kamanaka M. , Enslen H. , Dong C. , Wysk M. , Davis R.J. , Flavell R.A.
EMBO Rep.3:785-791(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION IN REGULATION OF T-CELL APOPTOSIS
4.

"Involvement of MKK6 in TCRalphabeta(int)CD69lo: a target population for apoptotic cell death in thymocytes."
Suzuki H. , Wu J. , Hossain K. , Ohhata T. , Du J. , Akhand A.A. , Hayakawa A. , Kimura H. , Hagiwara M. , Nakashima I.
FASEB J.17:1538-1540(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION IN REGULATION OF T-CELL APOPTOSIS
5.

"Mechanism of p38 MAP kinase activation in vivo."
Brancho D. , Tanaka N. , Jaeschke A. , Ventura J.J. , Kelkar N. , Tanaka Y. , Kyuuma M. , Takeshita T. , Flavell R.A. , Davis R.J.
Genes Dev.17:1969-1978(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION OF THE P38 MAP KINASE SIGNAL TRANSDUCTION PATHWAY
6.

"Negative feedback regulation of MKK6 mRNA stability by p38alpha mitogen-activated protein kinase."
Ambrosino C. , Mace G. , Galban S. , Fritsch C. , Vintersten K. , Black E. , Gorospe M. , Nebreda A.R.
Mol. Cell. Biol.23:370-381(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INDUCTION
7.

"Activation of mitogen-activated protein kinase kinase (MKK) 3 and MKK6 by type I interferons."
Li Y. , Batra S. , Sassano A. , Majchrzak B. , Levy D.E. , Gaestel M. , Fish E.N. , Davis R.J. , Platanias L.C.
J. Biol. Chem.280:10001-10010(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ENZYME REGULATION;FUNCTION OF THE P38 MAP KINASE SIGNAL TRANSDUCTION PATHWAY
8.

"Osteoclast differentiation requires TAK1 and MKK6 for NFATc1 induction and NF-kappaB transactivation by RANKL."
Huang H. , Ryu J. , Ha J. , Chang E.J. , Kim H.J. , Kim H.M. , Kitamura T. , Lee Z.H. , Kim H.H.
Cell Death Differ.13:1879-1891(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION OF THE P38 MAP KINASE SIGNAL TRANSDUCTION PATHWAY
9.

"Constitutive activation of MKK6 in chondrocytes of transgenic mice inhibits proliferation and delays endochondral bone formation."
Zhang R. , Murakami S. , Coustry F. , Wang Y. , de Crombrugghe B.
Proc. Natl. Acad. Sci. U.S.A.103:365-370(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION OF THE P38 MAP KINASE SIGNAL TRANSDUCTION PATHWAY
10.

"Differential activation of p38MAPK isoforms by MKK6 and MKK3."
Remy G. , Risco A.M. , Inesta-Vaquera F.A. , Gonzalez-Teran B. , Sabio G. , Davis R.J. , Cuenda A.
Cell. Signal.22:660-667(2010) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
11.

"Signaling by dual specificity kinases."
Dhanasekaran N. , Premkumar Reddy E.
Oncogene17:1447-1455(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: REVIEW ON ENZYME REGULATION;REVIEW ON FUNCTION

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